导师简介
更新日期：2026年4月2日
姓名：李圆圆
Email：liyuanyuan@sus.edu.cn
职称：副教授、硕导
所属学系/中心：国家兴奋剂检测上海实验室
研究方向：基于HPLC-HRMS/MS的蛋白质（组学）/小分子药物分离与分析、光谱分析
个人简介：
毕业于东北大学分析化学专业，获理学博士学位（硕博连读），国家蛋白质科学中心-北京联合培养博士研究生。近些年以第一作者和通讯作者（含共同）在《Analytical Chemistry》、《Food Chemistry》、《Chinese Chemical Letters》、《ACS Sensors》等期刊发表SCI论文10余篇，已授权国家发明专利五项。作为课题负责人和子课题负责人主持省部级项目2项，并主持上海市Ⅳ类高峰学科、ok138太阳集团青年科学基金各一项。当前具体研究方向包括1、基于HPLC-HRMS/MS的蛋白质（组学）/小分子药物分离与分析研究；2、食品和环境中新兴风险因子的快速检测研究（光谱分析方向）。
近些年以第一和通讯（含共同）发表SCI论文：
（1）Yuanyuan Li, Hang Li*, Yuping Xie, Shuo Chen, Ritian Qin, Hangyan Dong, Yongliang Yu*, Jianhua Wang, Xiaohong Qian, Weijie Qin*. An Integrated Strategy for Mass Spectrometry-Based Multiomics Analysis of Single Cells. Analytical Chemistry 93.42 (2021): 14059-14067.（第一作者，一区TOP）
（2）Yuanyuan Li, Chaoshuang Xia, Hongxian Zhao, Yuping Xie, Yangjun Zhang, Wanjun Zhang*, Yongliang Yu*, Jianhua Wang, Weijie Qin*. A new photolabeling probe for efficient enrichment and deep profiling of cell surface membrane proteome by mass spectrometry. Chinese Chemical Letters 34.2 (2023): 107377. （第一作者，一区TOP）
（3）Yuanyuan Li#, Na Zhou#, Jiayu Yan, Kaixin Cui, Qiqi Chu, Xi Chen, Xiaojun Luo*, Xiaojun Deng*. A dual-signaling surface-enhanced Raman spectroscopy ratiometric strategy for ultrasensitive Hg2+ detection based on Au@ Ag/COF composites. Food chemistry 456 (2024): 139998. （共同第一作者，一区TOP）
（4）Yang Wang#, Boyan Gao#, Yuanyuan Li#, Changzhi Shi, Hui Li, Zecang You, Mingliang Fang, Chenxu Wang, Xiaojun Deng*, Bing Shao*. Recent advances in nontargeted screening of chemical hazards in foodstuffs. Annual Review of Food Science and Technology 16.1 (2025): 195-218. （共同第一作者，一区TOP）
（5）Yuanyuan Li*, Jiayi Peng, Hong Chen, Weiling Yue, Yixuan Liu, Xiaojun Luo*, Lu Yang*. Shape-controlled asymmetric bowl-like PDA@ Au substrates for sensitive SERS detection of anabolic androgenic steroids. Talanta 287 (2025): 127604.（第一作者+共同通讯，一区TOP）
（6）Yuanyuan Li*, Wei Lin, Ziling Zheng, Xiaojun Luo*, Hong Chen*.Ultrasensitive detection of recombinant human erythropoietin-α via Au@ ES-COF surface-enhanced Raman scattering platform and circular DNA strand displacement reactions. Microchemical Journal (2025): 114788. （第一作者+共同通讯，二区TOP）
（7）Jiayu Yan#, Wei Lin#, Shifei Wang, Hong Chen, Xiaojun Luo*, Yuanyuan Li*, Xiaojun Deng*. Ratiometric SERS aptasensor with catalytic hairpin assembly amplification for sensitive detection of fibroblast growth factor 2. Sensors and Actuators B: Chemical (2025): 138708. （共同通讯，一区TOP）
（8）Jiayu Yan, Shifei Wang, Shisheng Xiong, Xiaojun Luo*, Yuanyuan Li*, Xiaojun Deng*. Cas12a Trans-Cleavage of Hairpins Triggers a CHA Cascade for an Ultrasensitive SERS Aptasensor. ACS sensors 11(2026), 2828−2839. （共同通讯，一区TOP）
（9）Shifei Wang, Jiayu Yan, Qin Chen*, Xiaodong Sun*, Yuanyuan Li*, Xiaojun Deng*. A SERS aptasensor based on highly specific recognition tags of PB@ AuNF nanoparticles for interference-free rapid detection of Gliadin. Food Control (2025): 111867. （共同通讯，一区TOP）
（10）Yalin Xie, Rui Tan, Min Hu, Xiaojun Luo*, Xiaojun Deng*, Yuanyuan Li*. Rapid and sensitive detection of prohibited diuretics using silver nanostar-enhanced SERS. Journal of Food Composition and Analysis (2025): 108265. （共同通讯，二区TOP）
（11）Yueyue Ma#, Na Zhou#, Zhichao Xia, Yushi Shen, Tao Yang, Xiaojun Luo*, Yuanyuan Li*. Surface-enhanced Raman spectroscopy facilitates the detection of multiple metabolic modulators. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 337 (2025): 126121. （共同通讯，二区TOP）
（12）Rui Tan, Mei Zeng, Qiuwen Huang, Na Zhou, Mengjiang Deng, Yuanyuan Li*, Xiaojun Luo*. Dual-mode SERS/colorimetric sensing of nitrite in meat products based on multifunctional au NPs@COF composite. Food chemistry 457 (2024): 140166. （共同通讯，一区TOP）
（13）Liping Chen, Xuanjiang Zeng, Fan Yang, Tao Yang, Yushi Chen, Yan Zhao*, Xiaojun Luo*, Yuanyuan Li*. Rapid and sensitive detection of mutations in SARS-CoV-2 by surface-enhanced Raman spectroscopy. Langmuir 41.5 (2025): 3583-3591. （共同通讯，二区）
（14）Ying Dong, Xue Yuan, Kaiyi Zhuang, Yuanyuan Li*, Xiaojun Luo*. Simultaneous and sensitive detection of SARS-CoV-2 proteins spike and nucleocapsid based on long-range SERS biosensor. Analytica Chimica Acta 1287 (2024): 342070. （共同通讯，一区TOP）
（15）Yalin Xie, Chenxi Yi, Qun Zhou, Min Hu, Panjie Li*, Xiaojun Luo*, Yuanyuan Li*. Magnetic organic frame material Fe3O4@ Au/COF for sensitive SERS detection and photo-Fenton degradation of tetracycline. Journal of Environmental Chemical Engineering (2025): 119472. （共同通讯，二区TOP）
